Key result
The Hypotension Prediction Index accurately predicted intraoperative hypotension 5 minutes before an event (AUC 0.926; 95% CI 0.925-0.926), performing superior to other hemodynamic variables.
Why the study?
Intraoperative hypotension is associated with worse perioperative outcomes in major noncardiac surgery, but the diagnostic ability of the arterial waveform-derived Hypotension Prediction Index relative to common hemodynamic variables was unproven.
Does the Hypotension Prediction Index accurately predict impending intraoperative hypotension compared to other hemodynamic variables in patients undergoing major surgery?
Comparison
Hypotension Prediction Index vs other commonly collected perioperative hemodynamic variables
Design
2-center retrospective analysis
Authors
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HPI may enable proactive management in major surgery; leaves open whether it improves outcomes in randomized trials.
Observational (n=255)
Yes
Does the Hypotension Prediction Index accurately predict impending intraoperative hypotension compared to other hemodynamic variables in patients undergoing major surgery?
Effect estimate: AUC 0.926 (95% CI 0.925-0.926)
The Hypotension Prediction Index provides accurate, continuous prediction of impending intraoperative hypotension up to 15 minutes before its occurrence, outperforming standard hemodynamic variables.
Davies et al. (2019) conducted an observational in Intraoperative hypotension (n=255). Hypotension Prediction Index vs. Other commonly measured perioperative hemodynamic variables was evaluated on Prediction of impending intraoperative hypotension 5 minutes before an event (AUC 0.926, 95% CI 0.925-0.926). The Hypotension Prediction Index accurately predicted intraoperative hypotension 5 minutes before an event (AUC 0.926; 95% CI 0.925-0.926), performing superior to other hemodynamic variables.
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