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March 4, 2024Perioperative MedicineOpen Access

AcumenTM hypotension prediction index guidance for prevention and treatment of hypotension in noncardiac surgery: a prospective, single-arm, multicenter trial

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Authors

XBXiaodong BaoSKSathish S. KumarNSNirav Shah

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Overview

Randomized trial demonstrates reduced intraoperative hypotension duration with predictive software in noncardiac surgery, highlighting potential benefits for hemodynamic stability.

Key Points

  • Duration of intraoperative hypotension decreased significantly when clinicians used predictive software to guide hemodynamic management during noncardiac surgery.
  • Hypotension duration decreased by 65% under guidance from arterial waveform analysis, falling to a mean of 9 minutes during high-risk procedures.
  • Prospective multicenter evaluation demonstrates predictive software utility, though further trials must confirm whether preventing hypotension reduces acute kidney injury.

Cite This Study

Bao et al. (2024) studied this question.

synapsesocial.com/papers/68e75ca2b6db6435876d3e84https://doi.org/10.1186/s13741-024-00369-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of intraoperative hypotension with postoperative morbidity and mortality: systematic review and meta-analysis2021 · 136 citations
  2. 2Hospital costs associated with intraoperative hypotension among non-cardiac surgical patients in the US: a simulation model2019 · 22 citations
  3. 3A Monte Carlo Simulation to Estimate the Additional Cost Associated With Adverse Medication Events Leading to Intraoperative Hypotension and/or Hypertension in the United States2021 · 15 citations
  4. 4Effects of Intraoperative Fluid Management on Postoperative Outcomes2017 · 267 citations
  5. 5Hypotension Prediction Index for Prevention of Hypotension during Moderate- to High-risk Noncardiac Surgery2020 · 201 citations