Key result
Low HDL cholesterol was an independent predictor of both increased left ventricular mass and diastolic dysfunction in patients with treated essential hypertension.
Why the study?
Is low HDL cholesterol associated with left ventricular hypertrophy and diastolic dysfunction in patients with treated essential hypertension?
Observational (n=274)
Is low HDL cholesterol associated with left ventricular hypertrophy and diastolic dysfunction in patients with treated essential hypertension?
Low HDL cholesterol is independently associated with unfavorable modifications in left ventricular structure and diastolic function in patients with treated essential hypertension.
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Hypothesis-generating for HDL in hypertensive heart disease; prospective studies needed before considering therapeutic implications.
T. Horio (2003) conducted an observational in Treated essential hypertension (n=274). Low HDL cholesterol was evaluated on Left ventricular mass and diastolic function (A/E ratio and deceleration time). Low HDL cholesterol was an independent predictor of both increased left ventricular mass and diastolic dysfunction in patients with treated essential hypertension.
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