Key result
Reduced nighttime decline in systolic blood pressure was significantly correlated with the occurrence of lacunar infarction in a logistic regression analysis.
Why the study?
Is reduced circadian blood pressure variation associated with the occurrence of lacunar infarction in hospitalized patients older than 55 years?
Population
118 hospitalized patients older than 55 years (61 with lacunar infarction and 57 control patients)
Comparison
Reduced circadian blood pressure variation vs Normal circadian blood pressure variation
Design
Case-control
Authors
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Observational data preclude practice change; leaves open causal role of blunted nocturnal BP dipping in lacunar infarction.
Case-Control (n=118)
Is reduced circadian blood pressure variation associated with the occurrence of lacunar infarction in hospitalized patients older than 55 years?
Reduced nighttime decline in systolic blood pressure is an important risk factor for the development of lacunar infarction, independent of absolute blood pressure levels and age.
Kukla et al. (1998) conducted a case-control in Lacunar infarction (n=118). Circadian blood pressure patterns (reduced nighttime decline) vs. Control patients without lacunar infarction was evaluated on Occurrence of lacunar infarction. Reduced nighttime decline in systolic blood pressure was significantly correlated with the occurrence of lacunar infarction in a logistic regression analysis.
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