Key result
Candesartan cilexetil is a highly effective angiotensin receptor blocker for the treatment of arterial hypertension and heart failure, with suggested benefits in several other conditions.
Why the study?
Does candesartan cilexetil improve outcomes in patients with arterial hypertension, heart failure, and other cardiovascular or renal conditions?
Does candesartan cilexetil improve outcomes in patients with arterial hypertension, heart failure, and other cardiovascular or renal conditions?
This review summarizes the evidence supporting candesartan cilexetil as an effective treatment for hypertension, heart failure, and potentially other cardiovascular and renal conditions.
Affirms candesartan for hypertension and HF; leaves suggested benefits in other conditions hypothesis-generating.
INTRODUCTION: Candesartan cilexetil is one of the most often-used first-line drugs regarding the management of arterial hypertension. Moreover, this drug has proven its effectiveness in chronic heart failure and exerts beneficial effects in diabetes, stroke, dementia and atrial fibrillation. AREAS COVERED: This review focuses on the use of candesartan cilexetil in Phase II and Phase III trials and their implications for clinical usage in the treatment of arterial hypertension and heart failure. The usage of candesartan cilexetil in patients with stroke, migraine or atrial fibrillation, hypertrophy obstructive or nonobstructive cardiomyopathy and diabetic or non diabetic renal diseases will be discussed. Relevant publications were identified by an extensive Medline search. EXPERT OPINION: Candesartan cilexetil is a highly effective ARB for the treatment of arterial hypertension and heart failure. Also, recent trials have suggested beneficial effects in diabetic patients, patients with nondiabetic renal diseases, stroke, migraine and atrial fibrillation.
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Joost et al. (2011) conducted a review in Arterial hypertension and heart failure. Candesartan cilexetil was evaluated. Candesartan cilexetil is a highly effective angiotensin receptor blocker for the treatment of arterial hypertension and heart failure, with suggested benefits in several other conditions.
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