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July 1, 1989International Journal of Technology Assessment in Health Care

Randomized Clinical Trials in Surgery

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Key result

This review discusses methodological issues, design pitfalls, and strategies to strengthen causal inference and improve the feasibility of randomized clinical trials in surgery.

Design

Review

Authors

BMBucknam McPeekFMFrederick MostellerMMMartin F. McKneally

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Overview

Alerts surgeons to RCT design pitfalls; leaves open validation of strategies to strengthen causal inference.

PICO

P
Population
Surgery

This article provides a methodological overview of designing, executing, and analyzing randomized clinical trials in surgery.

Cite This Study

McPeek et al. (1989) conducted a review in Surgery. This review discusses methodological issues, design pitfalls, and strategies to strengthen causal inference and improve the feasibility of randomized clinical trials in surgery.

synapsesocial.com/papers/6a16567bb11859caecb8e65bhttps://doi.org/10.1017/s026646230000739x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Issues in Surgical Randomized Controlled Trials1999 · 183 citations
  2. 2The Darker Side of Randomized Trials2012 · 36 citations
  3. 3Surgery and the randomised controlled trial: past, present and future1998 · 117 citations
  4. 4Randomized Trials in Surgery: How Far Have We Come?2012 · 20 citations
  5. 5Randomised Trials in Surgery: The Burden of Evidence2012 · 45 citations