Key result
This review examines the factors affecting patient recruitment into randomized controlled trials for conditions that can be treated with surgical or nonsurgical methods.
This review highlights the challenges and factors affecting patient recruitment in randomized controlled trials, particularly those comparing surgical and nonsurgical treatments.
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Trialists should address identified recruitment barriers in surgical-nonsurgical RCTs; leaves open effective mitigation strategies.
Randomized trials are thought to provide optimal evidence if carried out correctly. Their application to important questions is the best guide to clinical decision-making. However, these trials are expensive to complete and have a variety of challenges in design and application. This article will review some of the factors that affect our ability to recruit patients into randomized controlled trials for conditions that may be treated surgically by different methods or for conditions for which both nonsurgical and surgical treatments exist.
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Sibai et al. (2012) conducted a review in Conditions treated surgically or nonsurgically. This review examines the factors affecting patient recruitment into randomized controlled trials for conditions that can be treated with surgical or nonsurgical methods.
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