Key result
Acute myocarditis with preserved ejection fraction was associated with significantly impaired global endocardial longitudinal strain on admission compared to controls (-19.2 vs -24.0; P<0.0001).
Why the study?
Does left ventricular endocardial longitudinal dysfunction persist over time in patients with acute myocarditis and preserved ejection fraction?
Population
35 male patients with acute myocarditis and preserved systolic function based on cardiac MRI, and 25 control…
Design
Cohort
Follow-up
22 months
Authors
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Impaired endocardial strain may flag subclinical involvement in acute myocarditis with preserved EF; leaves open its prognostic utility and need for prospective validation.
Cohort (n=60)
Does left ventricular endocardial longitudinal dysfunction persist over time in patients with acute myocarditis and preserved ejection fraction?
Absolute Event Rate: -19.2% vs -24%
p-value: p=< 0.0001
Endocardial longitudinal strain is impaired in acute myocarditis patients with preserved ejection fraction and persists over time, highlighting the utility of layer-specific strain imaging for long-term monitoring.
Bella et al. (2018) conducted a cohort in Acute myocarditis with preserved ejection fraction (n=60). Acute myocarditis vs. Healthy controls was evaluated on Global endocardial longitudinal strain (ENDO-LS) on admission (p=< 0.0001). Acute myocarditis with preserved ejection fraction was associated with significantly impaired global endocardial longitudinal strain on admission compared to controls (-19.2 vs -24.0; P<0.0001).