Key result
Alteplase is an effective thrombolytic for myocardial infarction and acute ischemic stroke when administered early, though percutaneous interventions are superseding its use in myocardial infarction.
Why the study?
What is the role of alteplase in the management of myocardial infarction and stroke?
Population
Patients with evolving myocardial infarction or acute stroke
Comparison
Alteplase (tissue type plasminogen activator) vs Streptokinase, percutaneous transluminal…
Design
Review
Authors
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Supports early alteplase in stroke; leaves open its role in MI with advancing PCI.
What is the role of alteplase in the management of myocardial infarction and stroke?
This review highlights the shifting clinical role of alteplase, noting its descendancy in myocardial infarction due to the superiority of percutaneous interventions, and its ascendancy as a critical early treatment for acute stroke.
Sheila A Doggrell (2001) conducted a review in Myocardial infarction and stroke. Alteplase vs. Streptokinase, PTCA/stenting was evaluated. Alteplase is an effective thrombolytic for myocardial infarction and acute ischemic stroke when administered early, though percutaneous interventions are superseding its use in myocardial infarction.
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