Key result
Non-invasive ventilation improves 6-minute walk distance by ~26 meters in heart failure patients.
Why the study?
Heart failure causes a decline in functional capacity, and non-invasive ventilation has been reported as an effective rehabilitation strategy to improve it.
Does non-invasive ventilation improve functional capacity and exercise tolerance in patients with heart failure?
Systematic Review (n=151)
Does non-invasive ventilation improve functional capacity and exercise tolerance in patients with heart failure?
Effect estimate: Mean difference 26.16 meters (95% CI 9.26 to 43.06)
Non-invasive ventilation effectively improves functional capacity and exercise tolerance, as measured by the 6-minute walk test, in patients with heart failure.
Supports NIV to enhance exercise tolerance in HF; confirms efficacy on 6MWT across randomized trials.
Introduction: Heart failure (HF) is a clinical syndrome in which the heart has a decrease in blood pumping capacity, progressing to hemodynamic, metabolic and cardiovascular changes. According to the progression of HF, individuals present a decline in functional capacity (FC). FC being one of the objectives of rehabilitation. Non-invasive ventilation (NIV) has been reported as an effective strategy for increasing FC. Objective: To review the use of NIV on the FC of patients with HF. Methods: This is a systematic review using the PICO strategy, with a search performed in the PubMed, Central, PeDro, SciELO and LILACS databases, with the descriptors heart failure, non-invasive ventilation and exercise tolerance added by the Boolean operators " AND" and "OR". Results: Seventeen articles were found after reading the title and abstract, seven of which were chosen according to the inclusion criteria, based on the evaluation of 151 patients aged between 50 and 77 years, who showed that NIV can be an effective approach to increase the FC. NIV was effective in improving the distance covered in the 6-minute walk test by 26.16 meters (95% CI 9.26 to 43.06). Conclusion: NIV was effective in improving the FC of individuals with HF.
No takes yet. Share an insight, caveat, or question.
Silva et al. (2025) conducted a systematic review in Heart failure (n=151). Non-invasive ventilation (NIV) was evaluated on Distance covered in the 6-minute walk test (Mean difference 26.16 meters, 95% CI 9.26 to 43.06). Non-invasive ventilation improved the distance covered in the 6-minute walk test by 26.16 meters (95% CI 9.26 to 43.06) in patients with heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: