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January 1, 1974Clinical Science

Maximum Acceleration of Blood from the Left Ventricle in Patients with Ischaemic Heart Disease

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Why the study?

Does maximum acceleration of blood from the left ventricle correlate with the severity of ischaemic heart disease in patients undergoing coronary angiography?

Population

12 patients undergoing diagnostic coronary angiography, including 3 with chest pain and no cardiac…

Design

Cross-sectional

Authors

EBEd BennettSwansea UniversityWEWendy ElseThe Alfred HospitalGMGraham MillerAnalog Devices (United States)

Discussion

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Implication

Hypothesis-generating for aortic flow metrics in CAD; cross-sectional data leave incremental value and practice change open.

Structured PICO

Does maximum acceleration of blood from the left ventricle correlate with the severity of ischaemic heart disease in patients undergoing coronary angiography?

P
Population
12 patients undergoing diagnostic coronary angiography, including 3 with chest pain and no cardiac abnormality, 4 with definite coronary artery disease, and 5 with severe coronary disease
I
Intervention
Measurement of maximum acceleration and peak velocity of blood in the aorta using a catheter tip velocity transducer
O
Outcome
Maximum acceleration and peak velocity of blood in the aortasurrogate

Maximum acceleration and peak velocity of blood in the aorta measured via catheter tip transducer correlate inversely with coronary artery disease severity and closely with ejection fraction.

Cite This Study

Bennett et al. (1974) studied this question.

synapsesocial.com/papers/6a16ac65798df06fa4b268e4https://doi.org/10.1042/cs0460049
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Ejection in Conscious Dogs:1966 · 202 citations
  2. 2Measurement of Instantaneous Blood Flow Velocity and Pressure in Conscious Man with a Catheter-Tip Velocity Probe1969 · 188 citations
  3. 3Quantification of function in normal and infarcted regions of the left ventricle1972 · 108 citations
  4. 4Assessment of left ventricular function by single plane cineangiographic volume analysis.1971 · 45 citations
  5. 5Blood Pressure and Flow in the Ascending Aorta of Conscious Dogs1967 · 84 citations