Key result
Low peak Paco2 (<35 mmHg) during exercise was the strongest independent predictor of cardiac death in stable heart failure patients (HR 4.65; 95% CI 1.695-12.751; P=0.003).
Why the study?
Does peak arterial CO2 partial pressure (Paco2) during exercise predict cardiac mortality in stable chronic heart failure patients?
Cohort (n=128)
Does peak arterial CO2 partial pressure (Paco2) during exercise predict cardiac mortality in stable chronic heart failure patients?
Effect estimate: HR 4.65 (95% CI 1.695-12.751)
p-value: p=0.003
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Low peak arterial CO2 partial pressure (<35 mmHg) during exercise is a strong independent predictor of cardiac mortality in patients with stable chronic heart failure, primarily accounting for the prognostic power of the Ve/Vco2 slope.
Guazzi et al. (2004) conducted a cohort in Chronic heart failure (n=128). Low peak Paco2 (<35 mmHg) was evaluated on Cardiac death (HR 4.65, 95% CI 1.695-12.751, p=0.003). Low peak Paco2 (<35 mmHg) during exercise was the strongest independent predictor of cardiac death in stable heart failure patients (HR 4.65; 95% CI 1.695-12.751; P=0.003).
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