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September 1, 1986The Journal of Infectious Diseases

Epidemiology of Central Nervous System Infections in Olmsted County, Minnesota, 1950-1981

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Authors

ANA. NicolosiUniversity of IowaWHW. Allen HauserCenter for Pain and the BrainEBEttore BeghiUniversità Cattolica del Sacro Cuore

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Implication

Epidemiological study describes incidence and mortality of CNS infections in a population from 1950-1981, suggesting rising rates, especially in children.

Key Points

  • The aim was to analyze the incidence and trends of central nervous system infections in Olmsted County from 1950 to 1981.
  • Identified and documented all CNS infection cases excluding poliomyelitis in Olmsted County.
  • Calculated adjusted incidence rates and case fatality ratios for various CNS infections.
  • Evaluated trends in incidence across different age groups over the study period.
  • Adjusted incidence rate for bacterial meningitis was 8.6 per 100,000 person-years, with a 10% case fatality ratio.
  • Cumulative incidence through age 80 was 2.3% for men and 1.5% for women.
  • Aseptic meningitis had an incidence rate of 10.9 per 100,000 person-years, while viral encephalitis had 7.4 with a 3.8% case fatality ratio.

Cite This Study

Nicolosi et al. (1986) studied this question.

synapsesocial.com/papers/6a16c88d2fcf950e000548fehttps://doi.org/10.1093/infdis/154.3.399
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Encephalitis and aseptic meningitis, Olmsted County, Minnesota, 1950–1981: I. Epidemiology1984 · 124 citations
  2. 2Bacterial Meningitis — A Review of Selected Aspects1965 · 253 citations
  3. 3BACTERIAL MENINGITIS IN URBAN AND RURAL TENNESSEE11974 · 51 citations
  4. 4Cerebrospinal Fluid in Diseases of the Nervous System.1980 · 658 citations
  5. 5RE: “ESTIMABILITY AND ESTIMATION IN CASE-REFERENT STUDIES”1977 · 1,548 citations