Key result
Acute exercise at both moderate and heavy intensities significantly reduced postprandial triacylglycerol concentrations compared to rest after a high-fat meal.
Why the study?
Does moderate or heavy-intensity exercise reduce postprandial lipemia, oxidative stress, and endothelial dysfunction after a high-fat meal in healthy young men?
RCT (n=11)
Single-blind
Randomly assigned crossover
No
Does moderate or heavy-intensity exercise reduce postprandial lipemia, oxidative stress, and endothelial dysfunction after a high-fat meal in healthy young men?
p-value: p=<0.004
Acute exercise prior to a high-fat meal reduces postprandial lipemia, with heavy-intensity exercise offering greater protection against triglyceride spikes, while moderate-intensity exercise attenuates oxidative damage and improves fasting endothelial function.
Acute exercise before high-fat meals attenuates TAG rises; confirms benefits of both intensities and extends evidence for preprandial timing.
The aim of this study was to compare the effects of 2 different exercise intensities on postprandial lipemia, oxidative stress markers, and endothelial function after a high-fat meal (HFM). Eleven young men completed 2-day trials in 3 conditions: rest, moderate-intensity exercise (MI-Exercise) and heavy-intensity exercise (HI-Exercise). Subjects performed an exercise bout or no exercise (Rest) on the evening of day 1. On the morning of day 2, an HFM was provided. Blood was sampled at fasting (0 h) and every hour from 1 to 5 h during the postprandial period for triacylglycerol (TAG), thiobarbituric acid reactive substance (TBARS), and nitrite/nitrate (NOx) concentrations. Flow-mediated dilatation (FMD) was also analyzed. TAG concentrations were reduced in exercise conditions compared with Rest during the postprandial period (P < 0.004). TAG incremental area under the curve (iAUC) was smaller after HI-Exercise compared with Rest (P = 0.012). TBARS concentrations were reduced in MI-Exercise compared with Rest (P < 0.041). FMD was higher in exercise conditions than Rest at 0 h (P < 0.02) and NOx concentrations were enhanced in MI-Exercise compared with Rest at 0 h (P < 0.01). These results suggest that acute exercise can reduce lipemia after an HFM. However, HI-Exercise showed to be more effective in reducing iAUC TAG, which might suggest higher protection against postprandial TAG enhancement. Conversely, MI-Exercise can be beneficial to attenuate the susceptibility of oxidative damage induced by an HFM and to increase endothelial function in the fasted state compared with Rest.
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Krüger et al. (2016) conducted an RCT in Healthy (n=11). Moderate-intensity and heavy-intensity exercise vs. Rest was evaluated on Postprandial triacylglycerol (TAG) concentrations (p=<0.004). Acute exercise at both moderate and heavy intensities significantly reduced postprandial triacylglycerol concentrations compared to rest after a high-fat meal.
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