March 28, 2015AJP Heart and Circulatory PhysiologyOpen Access

Exercise intensity and the protection from postprandial vascular dysfunction in adolescents

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Why the study?

Does high-intensity interval exercise prevent postprandial vascular dysfunction after a high-fat meal better than moderate-intensity exercise or rest in adolescents?

Structured PICO

Does high-intensity interval exercise prevent postprandial vascular dysfunction after a high-fat meal better than moderate-intensity exercise or rest in adolescents?

Population

20 adolescents, mean age 14.3 ± 0.3 years, 10 male.

Intervention

High-intensity interval exercise (HIIE; 8 × 1 min cycling at 90% peak power with 75 s recovery) or moderate-intensity exercise (MIE; cycling at 90% of gas exchange threshold) performed 1 hour before consuming a high-fat meal (1.50 g/kg fat).

Comparator

Rest (CON) 1 hour before consuming the same high-fat meal.

Outcome

Macrovascular and microvascular endothelial function assessed by flow-mediated dilation (FMD) and laser Doppler imaging (peak reactive hyperemia [PRH]) 3 hours after the high-fat meal.surrogate

High-intensity interval exercise provides superior protection against postprandial vascular dysfunction following a high-fat meal compared to moderate-intensity exercise in adolescents.

Authors

BBBert BondUniversity of Exeter PGPhillip E. GatesUniversity of Exeter SJSarah R. JackmanUniversity of Exeter

Discussion

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Implication

HIIE may attenuate postprandial endothelial dysfunction in adolescents; leaves open effects on clinical outcomes.

Cite This Study

Bond et al. (2015) studied this question.

synapsesocial.com/papers/6a73cb2f2212a44d888de655 https://doi.org/10.1152/ajpheart.00074.2015

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