What question did this study set out to answer?

To determine whether gated equilibrium radionuclide angiography can accurately calculate left ventricular end-diastolic and end-systolic volumes in comparison with biplane contrast angiography.

September 1, 1979CirculationOpen Access

Left ventricular volumes by gated equilibrium radionuclide angiography: a new method.

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Authors

RSRobert A. SlutskyUniversity of San Diego JKJoel S. KarlinerSchreiner University DRDonald R. RicciInterventional Cardiology

Discussion

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Implication

Comparative imaging study reveals radionuclide angiography accurately measures left ventricular volumes in cardiac patients, indicating a reliable geometric-independent assessment method.

Key Points

To determine whether gated equilibrium radionuclide angiography can accurately calculate left ventricular end-diastolic and end-systolic volumes in comparison with biplane contrast angiography.
Assessed 52 patients with equilibrium radionuclide angiography using 99mTc-human serum albumin within 48 hours of biplane contrast angiography.
Extracted peak end-diastolic and nadir end-systolic counts from 20–28 frame time-activity curves and normalized counts by dose per body surface area, plasma volume, and plasma radioactivity concentration (counts/ml).
Calibrated and verified volume measurements using an experimental cardiac phantom.
Normalization by plasma counts/ml achieved the highest accuracy against biplane angiography (r = 0.98; SEE = ±11.5 ml for EDV, ±7.3 ml for ESV; N=17).
Normalization by dose per body surface area and plasma volume demonstrated correlations of r > 0.84 (N=35).
Phantom experiments demonstrated near-perfect correlation with known volumes (r = 0.99, SEE = ±6.5 ml).

Cite This Study

Slutsky et al. (1979) studied this question.

synapsesocial.com/papers/6a16ff022fcf950e00058767 https://doi.org/10.1161/01.cir.60.3.556

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September 1, 1979CirculationOpen Access

Left ventricular volumes by gated equilibrium radionuclide angiography: a new method.

View Full Paper

Ask AI

Bookmark

Authors

RSRobert A. SlutskyUniversity of San Diego JKJoel S. KarlinerSchreiner University DRDonald R. RicciInterventional Cardiology

Discussion

Member takes

Implication

Comparative imaging study reveals radionuclide angiography accurately measures left ventricular volumes in cardiac patients, indicating a reliable geometric-independent assessment method.

Key Points

To determine whether gated equilibrium radionuclide angiography can accurately calculate left ventricular end-diastolic and end-systolic volumes in comparison with biplane contrast angiography.
Assessed 52 patients with equilibrium radionuclide angiography using 99mTc-human serum albumin within 48 hours of biplane contrast angiography.
Extracted peak end-diastolic and nadir end-systolic counts from 20–28 frame time-activity curves and normalized counts by dose per body surface area, plasma volume, and plasma radioactivity concentration (counts/ml).
Calibrated and verified volume measurements using an experimental cardiac phantom.
Normalization by plasma counts/ml achieved the highest accuracy against biplane angiography (r = 0.98; SEE = ±11.5 ml for EDV, ±7.3 ml for ESV; N=17).
Normalization by dose per body surface area and plasma volume demonstrated correlations of r > 0.84 (N=35).
Phantom experiments demonstrated near-perfect correlation with known volumes (r = 0.99, SEE = ±6.5 ml).

Cite This Study

Slutsky et al. (1979) studied this question.

synapsesocial.com/papers/6a16ff022fcf950e00058767 https://doi.org/10.1161/01.cir.60.3.556

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