Key result
Pregnancy in Ebstein's anomaly proves well tolerated, carrying a ~10% MACE rate without maternal deaths.
Why the study?
Ebstein's anomaly is a rare congenital cardiac condition and data regarding pregnancy outcomes in this patient group are scarce.
What are the maternal and perinatal risks of pregnancy in women with Ebstein's anomaly?
Observational (n=81)
Yes
What are the maternal and perinatal risks of pregnancy in women with Ebstein's anomaly?
Most women with Ebstein's anomaly tolerate pregnancy well, but those with prepregnancy signs of heart failure are at higher risk for MACE.
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Supports counseling most women with Ebstein's anomaly on low pregnancy risk; leaves open prospective validation of heart failure predictors.
Zande et al. (2023) conducted an observational in Ebstein's anomaly (n=81). Pregnancy was evaluated on Major adverse cardiac event (MACE) defined as maternal mortality, heart failure, arrhythmia, thromboembolic event or endocarditis. Pregnancy in women with Ebstein's anomaly was generally well tolerated, with major adverse cardiac events occurring in 9.9% of pregnancies and no maternal deaths.
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