Why the study?
Do sodium lactate administration and hyperventilation reduce vagal tone in normal volunteers?
Do sodium lactate administration and hyperventilation reduce vagal tone in normal volunteers?
Withdrawal of parasympathetic activity, rather than just sympathetic activation, may contribute to the physiological changes seen in panic attacks.
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Vagal withdrawal may contribute to panic physiology; leaves open relevance to spontaneous attacks in patients.
David T. George (1989) studied this question.
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