Why the study?
Does intravenous sodium lactate infusion alter heart rate variability differently in patients with panic disorder compared to normal subjects?
Population
6 patients with panic disorder and 9 normal comparison subjects (n=15)
Comparison
Intravenous sodium lactate infusion vs Placebo infusion and normal comparison subjects
Design
Case-control
Authors
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Supports autonomic dysregulation in panic disorder; hypothesis-generating and should not yet change practice.
Does intravenous sodium lactate infusion alter heart rate variability differently in patients with panic disorder compared to normal subjects?
Patients with panic disorder exhibit exaggerated cardiac vagal withdrawal during lactate infusions compared to normal subjects.
Yeragani et al. (1994) studied this question.
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