Key result
Bidirectional cavopulmonary connection without additional pulmonary blood flow significantly increased mean oxygen saturation from 74.4% to 79.6% (p<0.01) and improved hemodynamics prior to TCPC.
Why the study?
Does bidirectional cavopulmonary connection without additional pulmonary blood flow improve hemodynamics and pulmonary artery development in patients with functional univentricular hearts?
Population
124 patients with functional univentricular hearts who underwent completion to a total cavopulmonary…
Design
Cohort
Follow-up
18.6+/-11.8 months between BCPC and TCPC
Authors
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Supports BCPC without APBF for univentricular palliation; hypothesis-generating and requires prospective trials before practice change.
Cohort (n=124)
No
Does bidirectional cavopulmonary connection without additional pulmonary blood flow improve hemodynamics and pulmonary artery development in patients with functional univentricular hearts?
Absolute Event Rate: 79.6% vs 74.4%
p-value: p=<0.01
Performing a bidirectional cavopulmonary connection without additional pulmonary blood flow results in favorable hemodynamics and pulmonary artery development for subsequent completion of a total cavopulmonary connection.
Schreiber et al. (2008) conducted a cohort in Functional univentricular hearts (n=124). Bidirectional cavopulmonary connection without additional pulmonary blood flow vs. Baseline (prior to BCPC) was evaluated on Mean oxygen saturation (p=<0.01). Bidirectional cavopulmonary connection without additional pulmonary blood flow significantly increased mean oxygen saturation from 74.4% to 79.6% (p<0.01) and improved hemodynamics prior to TCPC.
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