Key result
Past and repeated depression symptoms were associated with a reduction in left ventricular diastolic function (-8.3%; 95% CI -13.9% to -2.7% per 5 HADS-D units) in a healthy population.
Why the study?
Are previous, current, and repeated depression or anxiety symptoms associated with subclinical left ventricular dysfunction in a healthy population?
Population
1296 individuals free from known cardiovascular disease, hypertension, and diabetes
Comparison
Previous, current, and repeated depression or… vs Lower scores or absence of depression/anxiety…
Design
Cross-sectional
Authors
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Should not yet change clinical monitoring of diastolic function; leaves open causal and interventional effects in primary prevention.
Cross-Sectional (n=1,296)
Are previous, current, and repeated depression or anxiety symptoms associated with subclinical left ventricular dysfunction in a healthy population?
Effect estimate: Effect on e' -8.3% per 5 units (95% CI -13.9% to -2.7%)
Past and repeated depression symptoms are associated with subclinical left ventricular diastolic dysfunction in individuals without known cardiovascular disease.
Gustad et al. (2016) conducted a cross-sectional in Healthy population (n=1,296). Depression and anxiety symptoms was evaluated on Left ventricular diastolic function (e') and systolic function (longitudinal global strain) (Effect on e' -8.3% per 5 units, 95% CI -13.9% to -2.7%). Past and repeated depression symptoms were associated with a reduction in left ventricular diastolic function (-8.3%; 95% CI -13.9% to -2.7% per 5 HADS-D units) in a healthy population.
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