Key result
Total plasma catecholamines were significantly correlated with diastolic blood pressure in essential hypertension (p<0.01) and with plasma renin activity (r=0.497, p<0.001).
Population
55 patients with essential hypertension (EH) and 57 men undergoing elective vasectomy
Design
Cross-sectional
Authors
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Suggests sympathetic-renin link in hypertension but should not change practice; leaves open causal mechanisms.
Cross-Sectional (n=112)
p-value: p=<0.01
Increased sympathetic nerve tonicity and neurotransmitter biosynthesis are associated with blood pressure elevation in essential hypertension and may be linked to the renin-angiotensin system.
Miura et al. (1975) conducted a cross-sectional in Essential hypertension (n=112). Measurement of plasma catecholamines, DBH, and PRA was evaluated on Correlation of total plasma catecholamines with blood pressure (p=<0.01). Total plasma catecholamines were significantly correlated with diastolic blood pressure in essential hypertension (p<0.01) and with plasma renin activity (r=0.497, p<0.001).
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