Key result
Antihypertensive medication use at baseline was associated with a reduced incidence of dementia compared to no use (adjusted RR 0.7; 95% CI 0.6-1.0; P=0.03).
Why the study?
Does antihypertensive medication use reduce the occurrence and progression of dementia in a community population aged 75 years and older?
Cohort (n=1,810)
Does antihypertensive medication use reduce the occurrence and progression of dementia in a community population aged 75 years and older?
Effect estimate: RR 0.7 (95% CI 0.6-1.0)
p-value: p=0.03
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The use of antihypertensive medications, particularly diuretics, is associated with a reduced incidence and slower progression of dementia in elderly individuals.
Guo et al. (1999) conducted a cohort in Dementia (n=1,810). Antihypertensive medication vs. No antihypertensive medication was evaluated on Incidence of dementia (RR 0.7, 95% CI 0.6-1.0, p=0.03). Antihypertensive medication use at baseline was associated with a reduced incidence of dementia compared to no use (adjusted RR 0.7; 95% CI 0.6-1.0; P=0.03).
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