Key result
Combined baPWV, ABI, and FMD predicts coronary stenosis severity in hypertension with an AUC of 0.80.
Why the study?
Hypertension is a major risk factor for cardiovascular events, but the association of endothelial function and limb artery indices with coronary artery stenosis severity in hypertension needed analysis to identify high-risk patients.
Do endothelial function and limb artery indices (FMD, ABI, baPWV) predict coronary artery stenosis severity in patients with hypertension?
Observational
Do endothelial function and limb artery indices (FMD, ABI, baPWV) predict coronary artery stenosis severity in patients with hypertension?
Effect estimate: AUC 0.800
Combining brachial-ankle pulse wave velocity, ankle-brachial index, and flow-mediated vasodilation provides strong predictive value for identifying coronary artery stenosis severity in hypertensive patients.
May support noninvasive CAS assessment in hypertension; leaves open prospective validation before clinical use.
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Tao et al. (2024) conducted an observational in Hypertension and coronary artery stenosis. Endothelial function and limb artery indices (FMD, ABI, baPWV) was evaluated on Coronary artery stenosis severity (AUC 0.800). Combining brachial-ankle pulse wave velocity, ankle-brachial index, and flow-mediated vasodilatation predicted coronary artery stenosis severity in hypertensive patients with an AUC of 0.800.
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