Key result
Multidetector CT correlates well with 2D echo for assessing transmitral E/A in diastolic function.
Why the study?
While 2D echocardiography with TDI is commonly used to evaluate LV diastolic function, the utility of MDCT for assessing diastolic function has not been well studied.
Does 64-slice MDCT accurately assess transmitral and transannular flow velocities for evaluating diastolic function compared to 2D echocardiography in patients with known or suspected CAD?
Observational (n=40)
Blinded observers
Randomized order of examinations
Does 64-slice MDCT accurately assess transmitral and transannular flow velocities for evaluating diastolic function compared to 2D echocardiography in patients with known or suspected CAD?
Effect estimate: r=0.708
Absolute Event Rate: 1.26% vs 1.1%
p-value: p=<0.01
MDCT may be a feasible alternative for assessing left ventricular diastolic function by measuring transmitral and transannular flow velocities in patients undergoing cardiac CT for coronary artery disease evaluation.
Two-Dimensions (2D) echocardiography using TDI has been used most commonly to evaluate diastolic LV function. Although the role of MDCT imaging for evaluation of coronary atherosclerosis has been explored extensively. Moreover, assessment of LV volumes and systolic function using MDCT were studied before and showing accurate myocardial border delineation despite its clinical significance use regarding radiation and contrast. The probability to evaluate diastolic function using MDCT has not been studied well yet. The present study was aimed to evaluate the probability of cardiac CT for assessment of diastolic function in a direct comparison with 2-dimensional (2D) echocardiography using combined assessment of transmitral velocity and transannular mitral velocity. One hundred and twenty patients’ consecutive patients who had been referred for 64-MDCT imaging were prospectively selected from our clinical registry. After exclusion criteria had been applied, forty patients who had undergone 64-MDCT and 2D echocardiography with TDI were enrolled. MDCT and 2D echocardiography were performed within the same day and no acute coronary events or worsening of angina occurred between the examinations and no changes in the use of medication occurred between both examinations. A good correlation was found for demonstrate the probability of multidetector row computed tomography (MDCT) for assessment of trans-mitral flow velocities and trans-annular flow velocities in comparison with 2-dimensional (2D) echocardiography using tissue Doppler imaging (TDI).
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Basuoni et al. (2023) conducted an observational in Coronary Artery Disease (n=40). 64-slice Multidetector Row Computed Tomography (MDCT) vs. 2-Dimensional (2D) Echocardiography with Tissue Doppler Imaging (TDI) was evaluated on Transmitral velocity (E/A) (r=0.708, p=<0.01). Multidetector row computed tomography demonstrated a good correlation with 2-dimensional echocardiography for the assessment of transmitral velocity E/A (r=0.708, p<0.01) in evaluating diastolic function.
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