Why the study?
Does a colloid priming solution improve pulmonary oxygenation, central hemodynamics, or glomerular filtration compared to a non-colloid priming solution in patients undergoing cardiopulmonary bypass for aortic valve replacement?
Does a colloid priming solution improve pulmonary oxygenation, central hemodynamics, or glomerular filtration compared to a non-colloid priming solution in patients undergoing cardiopulmonary bypass for aortic valve replacement?
The use of a colloid priming solution during cardiopulmonary bypass for aortic valve replacement provides no clinical advantage over a non-colloid prime regarding oxygenation, hemodynamics, or renal function.
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No benefit of colloid prime seen in this cohort; should not change practice and leaves open randomized evaluation in bypass patients.
Öhqvist et al. (1981) studied this question.
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