Key result
Despite JNC8-compliant prescriptions, ~63% of hypertensive outpatients fail to achieve target blood pressure goals.
Why the study?
Hypertension is a major risk factor for cardiovascular disease, stroke, and chronic kidney disease, with cardiovascular disease being the leading cause of global mortality.
Cross-Sectional (n=86)
No
Despite moderate prescriber adherence to JNC8 guidelines, the majority of hypertensive outpatients in this Nigerian cohort failed to achieve target blood pressure goals and lacked indicated prophylactic statin or aspirin therapy.
Hypertension represents a substantial risk factor for the development of cardiovascular disease (CVD), stroke, and chronic kidney disease. CVD stands as the primary cause of global mortality. This study employed a prospective cross-sectional design spanning 4 weeks. Data were collected using a pro forma designed to capture patients’ sociodemographic and clinical information. Prescribers’ adherence to anti-hypertensive prescription guidelines, as per the JNC8 guideline, and patients’ attainment of target blood pressure (BP) goals were assessed. Framingham 10-year CVD risk score estimation was employed to estimate patients’ 10-year CVD risk levels. Among the patients, 51 (59.3%) had anti-hypertensive prescriptions that adhered to the JNC8 guidelines. However, a majority, 54 (62.8%), failed to achieve their JNC8 target BP goals, and 44 (51.2%) exhibited intermediate 10-year CVD risk levels. Furthermore, 71 (98.6%) of the patients did not receive the recommended statin and/or aspirin therapy, despite its necessity. An association was found between patients’ achievement of JNC8 target BP goals and their 10-year CVD risk levels. The majority of patients received anti-hypertensive prescriptions that aligned with JNC8 guidelines. Nonetheless, most of them did not attain their JNC8 target BP goals and exhibited intermediate to high 10-year CVD risk levels.
No takes yet. Share an insight, caveat, or question.
Samaila et al. (2024) conducted a cross-sectional in Hypertension (n=86). Anti-hypertensive medication was evaluated on Failure to achieve JNC8 target blood pressure goals. Although 59.3% of hypertensive outpatients received prescriptions complying with JNC8 guidelines, 62.8% failed to achieve target blood pressure goals and 51.2% had intermediate 10-year CVD risk.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: