Key result
Essential hypertension linked to ~48% greater renal sinus fat area versus normotensive controls.
Why the study?
Essential hypertension is a major modifiable cardiovascular risk factor, and excess visceral adipose tissue is associated with adverse metabolic risk factors.
Does the surface area of renal sinus fat measured by MDCT correlate with the presence and severity of essential hypertension and body mass index?
Cross-Sectional (n=80)
No
Does the surface area of renal sinus fat measured by MDCT correlate with the presence and severity of essential hypertension and body mass index?
Renal sinus fat surface area measured by MDCT correlates significantly with the presence and severity of essential hypertension and obesity, suggesting a potential link to cardiovascular risk.
Answers are grounded in this paper and cite their sources.
Renal sinus fat area was associated with hypertension; leaves open causal role in obesity-related risk, needing prospective validation.
Objectives: Essential hypertension remains a major modifiable risk factor for cardiovascular disease. Excess visceral adipose tissue is associated with the presence of adverse metabolic risk factors. Our study aims to measure the surface area of the renal sinus fat using MDCT and correlate the renal sinus surface area with the presence and grading of essential hypertension as well as body mass index. Materials and Methods: This cross-sectional study included two groups; the patients' group including 40 cases presented with a history of primary essential hypertension and the control group including 40 cases. The average of the surface area of the two kidneys as well as the average of the surface area of sinus fat was measured in the control and patient subgroups and was correlated with the presence and grading of essential hypertension as well as body mass index. Results: There was a significant correlation between the presence and grading of essential hypertension with prominent renal sinus fat. There was a significant correlation between the average surface area of kidneys and surface area of sinus fat in overweight and obese groups than in the control group (P < 0.01). Conclusion: Obesity is now recognized as a risk factor for the development of renal dysfunction. There was a significant correlation between the surface area of renal sinus fat measured using MDCT and the presence as well as grading of essential hypertension, suggesting that renal sinus fat may promote cardiovascular events.
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Abdeldayem et al. (2022) conducted a cross-sectional in Essential hypertension (n=80). Renal sinus fat area measurement using MDCT vs. Normotensive controls was evaluated on Median average surface area of renal sinus fat (mm2) (p=<0.001). Patients with essential hypertension had a significantly higher median surface area of renal sinus fat compared to normotensive controls (392.50 vs 265.30 mm2, p<0.001).
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