Key result
Hypertension is linked to ~21% higher renal sinus fat volume in middle-aged patients.
Why the study?
High blood pressure is a major public health problem, and this study aimed to examine the correlation between renal sinus fat volume and hypertension to explore its potential role in future management and screening.
Does renal sinus fat volume correlate with essential hypertension in middle-aged patients?
Does renal sinus fat volume correlate with essential hypertension in middle-aged patients?
Renal sinus fat volume is significantly increased in middle-aged patients with essential hypertension, suggesting a potential pathophysiological link or utility as a screening parameter.
Background and objectives: High blood pressure is a major public health problem related to the risk of heart disease, stroke and early death. The aim of this study is to examine the correlation between renal sinus fat volume and hypertension for participation in the future management of hypertension. It could be used as screening parameter for hypertension or decreasing renal sins fat volume as treatment of hypertension. Methods: This study was an observational cross-sectional implemented in the Rizgary teaching hospital/radiology department- Erbil City-Kurdistan region/Iraq, in a period between February. 2023 till November.2023. The participants were 98 visitors (referred by physicians for diagnoses of other medical issues), divided into hypertensive and non-hypertensive patients. Native abdominal CT scans were captured and by ellipsoid equation the renal sinus volume of each kidney was measured. Renal sinus volumes in each group were evaluated and compared. Result: The average size of renal sinus fat in left and right kidneys of hypertensive patients was 4.5814 ± 1.088 cm3 and 3.3802 ± 1.02547 cm3 respectively and in control group it was 3.8010 ± 1.10739 cm3 and 2.8004 ± 1.14657 cm3 respectively, it is significantly higher in patients with high blood pressure. There is a significant relationship between the presence of hypertension and renal sinus fat, more at the left kidney (P<0.001). Also, there is a clear difference in size of the renal sinus according to sex. Conclusion: Increased volume of renal sinus in middle-aged persons with essential hypertension, suggesting that there is a pathophysiological mechanism causing increasing volume of renal sinus fat in hypertensive people.
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Mahmood et al. (2026) studied this question. Renal sinus fat volume was significantly higher in hypertensive middle-aged patients (left kidney 4.58 cm³ vs 3.80 cm³; right kidney 3.38 cm³ vs 2.80 cm³) with P<0.001.
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