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May 28, 2026Discover FoodOpen Access

A systematic review of honey properties from antioxidant, anti-inflammatory, antidiabetic activities to cosmetic application and clinical trials

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Authors

HFHanane FerrassiYGYoussra El GhandouriYEYoussef Elouafy

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Overview

Systematic review summarizes honey's anti-inflammatory, antidiabetic, and antioxidant effects, suggesting therapeutic potential.

Key Points

  • This review aims to summarize and evaluate the therapeutic effects and biological activities of honey.
  • Conducted a literature search for studies on honey's properties.
  • Included both preclinical and clinical studies.
  • Analyzed data descriptively due to variability in study designs and honey types.
  • Honey exhibits anti-inflammatory effects by modulating inflammatory pathways, reducing pro-inflammatory mediators.
  • Reported antidiabetic effects include improved insulin sensitivity and reduced oxidative stress.
  • Antioxidant activity linked to flavonoids and phenolic compounds neutralizes free radicals and protects against oxidative damage.

Cite This Study

Ferrassi et al. (2026) studied this question.

synapsesocial.com/papers/6a17dbbe3fad632b0f9d87e9https://doi.org/10.1007/s44187-026-01045-1
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Also Consider

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  1. 1Antioxidant Capacity and Therapeutic Applications of Honey: Health Benefits, Antimicrobial Activity and Food Processing Roles2025 · 40 citations
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  3. 3Antioxidant Properties of Honey: Mechanisms and Clinical Applications2024 · 5 citations
  4. 4The effects of honey on pro‐ and anti‐inflammatory cytokines: A narrative review2021 · 68 citations
  5. 5Honey as a functional food: composition, bioactive compounds, health benefits and applications2026