The increasing demand for sustainable agricultural practices necessitates innovative approaches that integrate natural resources with advanced technologies. Phytochemicals, as bioactive compounds derived from plants, are widely recognized for their roles in enhancing crop productivity, pest resistance, and environmental resilience. Concurrently, green nanotechnology has emerged as a transformative tool, enabling the development of eco‐friendly nanomaterials via biogenic synthesis. This review offers an in‐depth appraisal of phytochemicals and their applications in sustainable agriculture, alongside the principles and significance of green nanotechnology in modern farming systems. Together, these technologies foster a paradigm shift toward agri‐nanotheranostic systems that unify diagnostics and therapeutics for precision agriculture. The synergistic application of phytochemicals and biogenic nanoparticles has the potential to enhance crop yields, improve soil health, manage pests and diseases, support livestock productivity, and reduce ecological footprints. Additionally, nanoencapsulation techniques protect bioactive compounds from degradation, ensuring efficient delivery in both crop and animal systems. Despite promising results, challenges, such as scalability, regulatory ambiguity, and limited long‐term safety data, persist. Addressing these limitations is critical toward ensuring the responsible adoption of these technologies. We emphasize the need for interdisciplinary collaboration, inclusive policy development, and technology transfer, especially in low‐ and middle‐income countries. Future perspectives highlight emerging innovations in nano‐enabled agriculture, including precision delivery systems, smart nanosensors, and integrated sustainable farming approaches. Together with global cooperation and a One Health perspective, integrating phytochemicals and green nanotechnology holds significant potential to advance sustainable food systems, enhancing climate resilience, food security, and ecological balance.
Ajose et al. (Thu,) studied this question.