Why the study?
Does dosage reduction of anticholinergic drugs improve cognitive function in elderly nursing home residents?
Population
34 randomly selected elderly nursing home residents
Comparison
Dosage reduction of anticholinergic drugs vs Nonintervention control subjects
Design
RCT, Randomly assigned to intervention or control group
Follow-up
4 weeks
Authors
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Supports deprescribing anticholinergics in elderly nursing home residents; extends antimuscarinic burden evidence to RCT cognitive outcomes.
Does dosage reduction of anticholinergic drugs improve cognitive function in elderly nursing home residents?
Reducing serum antimuscarinic activity through dosage reduction may improve cognitive function in elderly nursing home residents.
Tollefson et al. (1991) studied this question.
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