Key result
Nighttime systolic blood pressure variability on ambulatory monitoring was identified as an independent risk factor for coronary heart disease in diabetic hypertensive patients.
Why the study?
Is increased short-term blood pressure variability on ambulatory blood pressure monitoring associated with coronary heart disease in diabetic hypertensive patients?
Observational (n=72)
Is increased short-term blood pressure variability on ambulatory blood pressure monitoring associated with coronary heart disease in diabetic hypertensive patients?
Increased nighttime systolic blood pressure variability on ambulatory monitoring is an independent risk factor for coronary heart disease in diabetic hypertensive patients.
Answers are grounded in this paper and cite their sources.
Supports nighttime SBP variability as potential CHD risk marker in diabetic hypertension; hypothesis-generating and should not change practice yet.
We examined risk factors for coronary heart disease (CHD) by ambulatory blood pressure (BP) monitoring in 72 diabetic hypertensives who were hospitalized for the educational program. The patients were divided into two groups (CHD group, 19 subjects; and non-CHD group, 53 subjects) along with or without co-existing CHD. On ambulatory BP monitoring, no significant differences were found between the groups regarding BP values through the day. However, the CHD group had a significantly greater BP variability than non-CHD group. The result of logistic regression analysis demonstrated that nighttime systolic BP variability was an independent risk factor for CHD.
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Ozawa et al. (2009) conducted an observational in Diabetic hypertensives (n=72). Ambulatory blood pressure monitoring (nighttime systolic BP variability) vs. Patients without co-existing CHD was evaluated on Coronary heart disease (CHD). Nighttime systolic blood pressure variability on ambulatory monitoring was identified as an independent risk factor for coronary heart disease in diabetic hypertensive patients.
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