Key result
Myofibril assembly and maintenance in zebrafish share common properties with avian muscle, supporting the premyofibril model of myofibrillogenesis.
This study confirms that the premyofibril model of myofibrillogenesis applies to zebrafish skeletal muscle development, establishing it as a relevant model for muscle assembly.
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Supports zebrafish as a model for myofibrillogenesis; leaves open translation to mammalian cardiac muscle.
Sanger et al. (2009) studied Skeletal muscle development. Antibody staining and Fluorescence Recovery After Photobleaching was evaluated on Protein localization and exchange during myofibrillogenesis. Myofibril assembly and maintenance in zebrafish share common properties with avian muscle, supporting the premyofibril model of myofibrillogenesis.
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