Population
Foot-and-mouth disease virus (FMDV) cloned cDNA and Escherichia coli expression system
Comparison
Site-directed mutagenesis of the L gene and… vs Wild-type L protein
Design
Preclinical
Authors
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May guide FMDV antiviral targeting in livestock; leaves open extension to human picornaviruses.
The FMDV L protein functions as a viral protease responsible for its own cleavage from the viral polyprotein.
Strebel et al. (1986) studied this question.
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