Key result
Resveratrol increased survival and delayed the progression of cardiac remodeling in a murine myocardial infarction model by antagonizing the detrimental effects of fractalkine.
Resveratrol improves survival and attenuates cardiac remodeling in murine models of myocardial infarction by antagonizing the detrimental effects of fractalkine.
Hypothesis-generating for resveratrol in post-MI remodeling; prospective human studies needed before clinical consideration.
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Xuan et al. (2012) studied Myocardial ischemia and ischemic heart failure. Resveratrol vs. Vehicle alone / untreated was evaluated on Survival and cardiac remodeling (heart weight/body weight ratio, lung weight/body weight ratio, infarct size). Resveratrol increased survival and delayed the progression of cardiac remodeling in a murine myocardial infarction model by antagonizing the detrimental effects of fractalkine.
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