Key result
Ankle-brachial index in patients with peripheral arterial disease was significantly associated with aortic augmentation index (β=-11.5; P=.002) and subendocardial viability ratio (β=33.2; P=.036).
Cross-Sectional (n=65)
No
Effect estimate: β -11.5 (95% CI -18.6 to -4.5)
p-value: p=.002
In patients with stable peripheral arterial disease, the severity of lower limb perfusion impairment is significantly associated with central aortic pressure augmentation and subendocardial viability ratio, suggesting a pathophysiologic link to cardiac prognosis.
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May inform integrated vascular-cardiac assessment in PAD; leaves open prospective validation of prognostic utility.
Mosimann et al. (2012) conducted a cross-sectional in Peripheral arterial disease (n=65). Ankle-brachial arterial pressure index (ABI) was evaluated on Aortic augmentation index (AIx) (β -11.5, 95% CI -18.6 to -4.5, p=.002). Ankle-brachial index in patients with peripheral arterial disease was significantly associated with aortic augmentation index (β=-11.5; P=.002) and subendocardial viability ratio (β=33.2; P=.036).
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