Key result
4D flow CMR shows no significant bias between aortic and mitral stroke volumes in AF.
Why the study?
The role of 4D flow cardiovascular MRI in assessing trans-valvular flow in patients with AF had not previously been assessed.
Does four-dimensional flow cardiovascular MRI accurately quantify trans-valvular flow in patients with atrial fibrillation compared to healthy controls?
Cross-Sectional (n=18)
No
Does four-dimensional flow cardiovascular MRI accurately quantify trans-valvular flow in patients with atrial fibrillation compared to healthy controls?
Absolute Event Rate: 1.64% vs -4.8%
p-value: p=0.56
4D flow cardiovascular MRI is feasible and provides internally valid quantification of trans-valvular flow in patients with rate-controlled atrial fibrillation.
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Supports 4D flow MRI feasibility for valvular flow assessment in rate-controlled AF; extends validation data but leaves open need for larger prospective studies.
Mills et al. (2021) conducted a cross-sectional in Atrial fibrillation (n=18). Four-dimensional (4D) flow cardiovascular magnetic resonance imaging vs. Healthy controls in sinus rhythm was evaluated on Bias between aortic valve and mitral valve stroke volumes (95% CI -4.7 to 7.94, p=0.56). Four-dimensional flow cardiovascular MRI demonstrated no significant bias between aortic and mitral valve stroke volumes in patients with atrial fibrillation (bias 1.64 ml, p=0.56).
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