Key result
Postmenopausal healthy women had significantly higher hs-CRP levels (4.02 mg/L) compared to premenopausal women (1.81 mg/L), representing an approximately 3-fold increase.
Why the study?
Does postmenopausal status affect high-sensitivity C-reactive protein (hs-CRP) levels in healthy women?
Cross-Sectional (n=190)
No
Does postmenopausal status affect high-sensitivity C-reactive protein (hs-CRP) levels in healthy women?
Absolute Event Rate: 4.02% vs 1.81%
p-value: p=<0.05
Menopausal status was associated with higher hs-CRP; hypothesis-generating for cardiovascular risk assessment.
A high-sensitivity c-reactive protein (hs-CRP) is one of the acute phase proteins which remarkably increased in systemic inflammation and considered to be an independent risk factor for Cardio Vascular Diseases (CVD). The present study was conducted to evaluate the level of (hs-CRP) in pre and post menopausal women. Two study groups were enrolled in the present study .The first group included (100) samples from healthy pre menopausal woman of age ranged (27-45)years. The second group included (90) samples taken from healthy postmenopausal women their age ranged (51-67)years .The following Kit from (i-CHRomTM hs CRP-25) was used as an immunoassay pattern to evaluate hs-CRP from Boditech MedIne . The results of the present study showed a significant differences between the two groups under study , in which the level of hsCRP in pre-was( 1.81_+1.02) with a significant increase (p<0.05) in post menopausal women (4.02+_1.67mg/L).This study concludes that there is approximately 3 fold significant increase in hs-CRP levels in post menopausal Iraqi's women.
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Fatma Mustafa Mohammed (2016) conducted a cross-sectional in Healthy pre and post menopausal women (n=190). Postmenopausal status vs. Premenopausal status was evaluated on High-sensitivity C-reactive protein (hs-CRP) level (mg/L) (p=<0.05). Postmenopausal healthy women had significantly higher hs-CRP levels (4.02 mg/L) compared to premenopausal women (1.81 mg/L), representing an approximately 3-fold increase.
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