Key result
Exercise training provided no benefits and was associated with worse outcomes in heart failure patients with atrial fibrillation and cardiovascular implantable electronic devices.
Why the study?
Data are scarce regarding the efficacy and safety of exercise training in patients with HFrEF and atrial fibrillation who have a CRT-D or an ICD.
Does exercise training improve outcomes in patients with HFrEF, atrial fibrillation, and a CRT-D or ICD?
Does exercise training improve outcomes in patients with HFrEF, atrial fibrillation, and a CRT-D or ICD?
Exercise training may not be beneficial and could be associated with worse outcomes in the specific subgroup of HFrEF patients with concurrent atrial fibrillation and implantable defibrillators.
Answers are grounded in this paper and cite their sources.
Caution advised before changing exercise recommendations in this subgroup; leaves open need for randomized confirmation.
Background: Exercise training (ExT) in patients with heart failure and reduced ejection fraction (HFrEF) improves clinical condition and prognosis. Data are scarce regarding the efficacy and safety of ExT in patients with HFrEF and atrial fibrillation (AFib) and with a cardiac resynchronization therapy defibrillator (CRT-D) or an implantable cardioverter-defibrillator (ICD).
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Dąbrowski et al. (2018) studied this question. Exercise training provided no benefits and was associated with worse outcomes in heart failure patients with atrial fibrillation and cardiovascular implantable electronic devices.
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