Why the study?
The ideal duration of dual antiplatelet therapy following percutaneous coronary intervention remains unknown.
Does longer-term DAPT reduce MACE compared to shorter-term DAPT in patients following PCI?
Does longer-term DAPT reduce MACE compared to shorter-term DAPT in patients following PCI?
Longer-term DAPT after PCI reduces MACE but increases major bleeding compared to shorter-term DAPT.
Longer DAPT post-PCI requires individualized risk-benefit assessment for MACE reduction versus bleeding; confirms established duration trade-off in Level 1 evidence.
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Gelbenegger et al. (2021) studied this question.
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