Why the study?
Are patients and clinic personnel able to correctly guess treatment group assignment in a double-blind trial of propranolol versus placebo?
Are patients and clinic personnel able to correctly guess treatment group assignment in a double-blind trial of propranolol versus placebo?
The study demonstrates that blinding in the β-Blocker Heart Attack Trial was partially compromised, with clinic personnel likely using heart rate changes to guess treatment assignment.
Answers are grounded in this paper and cite their sources.
Blinding was partially compromised in this β-blocker RCT; challenges the validity of unverified double-blinding in similar trials.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Robert P. Byington (1985) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: