June 1, 2021International Journal of General MedicineOpen Access

A Specific Assessment of the Normal Anatomy of the Aortic Root in Relation to Age and Gender

View Full Paper

Ask AI

Bookmark

Why the study?

Normal reference values for aortic root dimensions on CCTA were lacking, and the influence of age and gender on these dimensions remained uncertain.

Population

1286 healthy individuals who underwent CCTA

Comparison

Comparisons across genders and seven age groups

Design

Retrospective study

Authors

XWXiang WangWeifang Medical University XRXinshuang RenQingdao University YAYunqiang AnChinese Academy of Medical Sciences & Peking Union Medical College

Discussion

Member takes

Implication

Supports age- and sex-specific CCTA aortic root norms in middle age; leaves open prospective validation before clinical adoption.

Structured PICO

Population

1,286 Chinese adults (mean age 52.7, 49.3% male) suspected of coronary artery disease but without aortic or aortic valve disease, heart failure, congenital heart disease, cardiomyopathy, left ventricular hypertrophy, atrial fibrillation, or hypertension, who underwent coronary computed tomography angiography (CCTA).

Outcome

Normal values and variations of aortic root dimensions (aortic annulus, sinus of Valsalva, sinotubular junction, LVOT, and ascending aorta) measured by CCTA, and their correlation with age and gender.surrogate

Aortic root dimensions measured by CCTA increase with age and, after body surface area correction, are larger in females than males, providing important reference values for structural interventions like TAVR.

Limitations

Small sample size in age groups <30 and ≥70 years
Single-center study in China, limiting generalizability to other ethnicities
Patients were suspected of coronary artery disease

Cite This Study

Wang et al. (2021) studied this question.

synapsesocial.com/papers/6a1975fdfa25ab5db6d98779 https://doi.org/10.2147/ijgm.s312439

View Full Paper

Ask AI

Bookmark

A Specific Assessment of the Normal Anatomy of the Aortic Root in Relation to Age and Gender

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

A Specific Assessment of the Normal Anatomy of the Aortic Root in Relation to Age and Gender

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider