Why the study?
Up-to-date reference values of transthoracic echocardiographic aortic root dimensions matched by sex, age, and body surface area were needed to support the diagnosis, monitoring, and treatment of aortic root disease.
What are the population-based reference values for transthoracic echocardiographic aortic root dimensions in healthy adults?
Population
1687 healthy subjects from the population-based Hamburg City Health Study cohort
Design
Population-based prospective cohort study
Key result
Absolute aortic root dimensions were significantly smaller in women than men, but indexing for body surface area reversed this effect, with age, sex, and body size being significant determinants.
Authors
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Supplies updated aortic root norms by sex, age, and BSA; extends prior references but leaves open clinical impact pending validation.
Cross-Sectional (n=1,687)
No
What are the population-based reference values for transthoracic echocardiographic aortic root dimensions in healthy adults?
This study provides updated, population-based reference values for aortic root dimensions assessed by transthoracic echocardiography, stratified by age, sex, and body surface area.
Wenzel et al. (2021) conducted a cross-sectional in Healthy adults (n=1,687). Transthoracic echocardiography was evaluated on Aortic root dimensions (aortic annulus, sinus of Valsalva, sinotubular junction, ascending aorta). Absolute aortic root dimensions were significantly smaller in women than men, but indexing for body surface area reversed this effect, with age, sex, and body size being significant determinants.