What question did this study set out to answer?

To calculate blood flow rate in dialysis vascular access by evaluating mathematical bolus tracking algorithms and curve-fitting functions applied to cine-angiographic and fluoroscopic image sequences.

September 26, 2021DiagnosticsOpen Access

Mathematical Models for Blood Flow Quantification in Dialysis Access Using Angiography: A Comparative Study

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Authors

NKNischal KoiralaThe Ohio State University GMGordon McLennanCleveland Clinic

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Implication

In vitro study demonstrates accurate blood flow quantification using cross-correlation angiography, suggesting feasibility for real-time monitoring during dialysis access salvage.

Key Points

To calculate blood flow rate in dialysis vascular access by evaluating mathematical bolus tracking algorithms and curve-fitting functions applied to cine-angiographic and fluoroscopic image sequences.
Assessed flow quantification in a flow phantom model using digital subtraction angiography (DSA at 3 and 6 frames/s) and fluoroscopy (4 and 10 pulses/s).
Calculated flow rates using peak-to-peak and cross-correlation bolus tracking algorithms combined with gamma-variate, lagged normal, and polynomial curve-fitting functions.
Validated computed flow rates and dye propagation distances against an in-line flow sensor.
The cross-correlation algorithm paired with gamma-variate curve fitting demonstrated the highest accuracy and lowest variability in both imaging modalities.
Mean absolute percent error was 21.4 ± 1.9% in DSA mode at 6 frames/s and 37.4 ± 3.6% in fluoroscopic mode at 10 pulses/s.
Radiation dose scaled linearly with frame rate in both modes and remained sufficiently low to prevent stochastic effects or tissue damage.

Cite This Study

Koirala et al. (2021) studied this question.

synapsesocial.com/papers/6a19b4514b45427442ea99e1 https://doi.org/10.3390/diagnostics11101771

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Implication

In vitro study demonstrates accurate blood flow quantification using cross-correlation angiography, suggesting feasibility for real-time monitoring during dialysis access salvage.

Mathematical Models for Blood Flow Quantification in Dialysis Access Using Angiography: A Comparative Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Mathematical Models for Blood Flow Quantification in Dialysis Access Using Angiography: A Comparative Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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