What does this research mean for the field?

The modified CINE inversion recovery (mCINE-IR) sequence is highly reproducible and sensitive enough to detect T1 changes in the rat myocardium at 7 Tesla. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

October 7, 2013Journal of Magnetic Resonance ImagingOpen Access

T1 mapping in the rat myocardium at 7 tesla using a modified CINE inversion recovery sequence

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Population

Gadolinium phantoms, a heart specimen, 1 healthy rat, and 2 cryo-infarcted rats

Design

Preclinical

Authors

HSHenk SmitJichi Medical University RPRubén Pellicer-GuridiThe University of Queensland JGJamal GuenounCambridge University Hospitals NHS Foundation Trust

Discussion

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Implication

Supports preclinical T1 mapping in rat models; leaves open translation to clinical use.

Structured PICO

Population

Gadolinium phantoms, a heart specimen, 1 healthy rat, and 2 cryo-infarcted rats

Intervention

Modified CINE inversion recovery (mCINE-IR) acquisition at 7 Tesla

Outcome

Reproducibility and sensitivity of myocardial T1 measurementssurrogate

The mCINE-IR sequence at 7 Tesla is highly reproducible and sensitive for detecting myocardial T1 changes in rat models, facilitating translational imaging studies.

Cite This Study

Smit et al. (2013) studied this question.

synapsesocial.com/papers/6a19b8a8407564563bf674f9 https://doi.org/10.1002/jmri.24251

Topics

Cardiac MRI

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T1 mapping in the rat myocardium at 7 tesla using a modified CINE inversion recovery sequence

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

T1 mapping in the rat myocardium at 7 tesla using a modified CINE inversion recovery sequence

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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