Why the study?
The study aimed to design a myocardial T1 quantification method in small laboratory animals and investigate the effects of spatiotemporal regularization and required acquisition duration.
Population
A phantom, a healthy rat, and rats in a small myocardium-remodeling study
Comparison
Self-gated inversion-recovery radial 2D/3D golden-angle stack-of-stars acquisition vs ground-truth method and literature values
Design
Preclinical imaging development and validation study
Authors
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Feasibility shown in small animals; leaves open clinical translation and validation of accelerated T1 mapping.
A novel compressed-sensing MRI method enables accurate myocardial T1 quantification in rats, distinguishing normal from remodeling tissue with acquisition times as short as 5-15 minutes.
Vitouš et al. (2023) studied this question.
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