Why the study?
Do pulsatile and steady 24-h blood pressure components predict cardiac events and left ventricular mass in young and middle-aged essential hypertensives?
Do pulsatile and steady 24-h blood pressure components predict cardiac events and left ventricular mass in young and middle-aged essential hypertensives?
A blunted nocturnal reduction in pulse pressure and higher average 24-hour pulse pressure identify hypertensive patients at increased risk for cardiac events.
May refine risk stratification in hypertension; leaves open whether targeting nocturnal pulse pressure dipping improves outcomes.
significance. Inclusion in the model of other independent determinants of cardiac events (age, gender, diabetes, smoking, left ventricular hypertrophy) did not affect results. In conclusion, for any level of daytime PP, a blunted reduction in PP from day to night identifies hypertensive subjects at increased risk for cardiac events. A comparable prognostic information is provided by the average 24-hour PP.
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Giuseppe Mulè (2003) studied this question.
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