Key result
Multichannel electrical impedance measurements estimated a time difference between ventricular contractions of 35 ms in a healthy subject, agreeing with theoretical values.
Why the study?
Can multichannel electrical impedance measurements accurately assess the time delay between ventricular contractions?
Case Report (n=1)
No
Can multichannel electrical impedance measurements accurately assess the time delay between ventricular contractions?
Multichannel electrical impedance measurements may offer a novel method for assessing ventricular dyssynchrony.
Answers are grounded in this paper and cite their sources.
Supports feasibility of multichannel impedance for ventricular timing; leaves open validation in dyssynchrony and clinical utility.
The paper presents a novel approach to assessment of ventricular dyssynchrony basing on multichannel electrical impedance measurements. Using a proper placement of electrodes, the sensitivity approach allows estimating time difference between chambers contraction from over determined nonlinear system of equations. The theoretical considerations which include Finite Element Method simulations were verified using measurements on healthy 28 year's old woman. The nonlinear least squares method was applied to obtain a time difference between heart chambers contraction. The obtained value was in a good agreement with theoretical values found in literature.
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Lewandowska et al. (2013) conducted a case report in Healthy (n=1). Multichannel electrical impedance measurements vs. Theoretical values from literature was evaluated on Time difference between chamber contractions (ms). Multichannel electrical impedance measurements estimated a time difference between ventricular contractions of 35 ms in a healthy subject, agreeing with theoretical values.
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