Key result
Intracardiac impedance measurement via a multipolar catheter allows for the continuous real-time assessment of myocardial contractility and effective heart rate modulation in permanent pacing systems.
Intracardiac impedance measurement provides a method for real-time assessment of myocardial contractility and enables effective heart rate modulation in permanent pacing systems.
May inform contractility-guided pacemaker development; leaves open effects on clinical outcomes.
By introducing an alternating current through the ventricular cavity via a multipolar catheter the potential difference measured between adjacent electrodes can be used to assess ventricular volume. This is possible by the measurement of intracardiac impedance. The data obtained can be used to construct pressure-volume loops allowing the continuous real-time assessment of myocardial contractility. Clinical applications of this research tool are now becoming apparent. Further derivations of impedance measurement have been incorporated into commercially available permanent pacing systems, allowing effective heart rate modulation.
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Arthur et al. (2000) conducted a review in Myocardial contractility and rhythm stability. Intracardiac impedance measurement was evaluated. Intracardiac impedance measurement via a multipolar catheter allows for the continuous real-time assessment of myocardial contractility and effective heart rate modulation in permanent pacing systems.
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